Comparison of the Effects of Omeprazole and Rabeprazole on Ticlopidine Metabolism In Vitro
نویسندگان
چکیده
منابع مشابه
Comparison of the effects of omeprazole and rabeprazole on ticlopidine metabolism in vitro.
The thienopyridine derivative ticlopidine (TCL) is an inhibitor of adenosine diphosphate-induced platelet aggregation. Combination therapy with a thienopyridine derivative and aspirin is standard after coronary stenting, although more hemorrhagic complications occur with the combination therapy than with aspirin alone. A proton pump inhibitor (PPI) is required for prevention or treatment of upp...
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ژورنال
عنوان ژورنال: Journal of Pharmacological Sciences
سال: 2011
ISSN: 1347-8613,1347-8648
DOI: 10.1254/jphs.11048fp